Reply to Robbins: Multi-breath washout tests: indices versus model parameters
نویسندگان
چکیده
منابع مشابه
Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests.
BACKGROUND Lung clearance index (LCI), a measure of ventilation inhomogeneity derived from the multiple-breath inert gas washout (MBW) technique, has been shown to detect abnormal lung function more readily than spirometry in preschool children with cystic fibrosis, but whether this holds true during infancy is unknown. OBJECTIVES To compare the extent to which parameters derived from the MBW...
متن کاملCYSTIC FIBROSIS Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
Sooky Lum, Per Gustafsson, Henrik Ljungberg, Georg Hülskamp, Andrew Bush, Siobhán B Carr, Rosemary Castle, Ah-fong Hoo, John Price, Sarath Ranganathan, John Stroobant, Angie Wade, Colin Wallis, Hilary Wyatt, Janet Stocks on behalf of the London Cystic Fibrosis Collaboration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ...
متن کاملEquipment for multiple breath washout.
5 Demeo DL, Campbell EJ, Barker AF, et al. IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. We read with interest the article ''Paediatrics in Berlin'' [1] in a recent issue of the European Respiratory Journal, which sum-marised the paediatric topics of the European Respiratory Society's Annual Congress in Berlin. In this article, inert gas mul...
متن کاملEvaluation of the Impact of Alveolar Nitrogen Excretion on Indices Derived from Multiple Breath Nitrogen Washout
BACKGROUND A large body of evidence has now accumulated describing the advantages of multiple breath washout tests over conventional spirometry in cystic fibrosis (CF). Although the majority of studies have used exogenous sulphur hexafluoride (SF6) as the tracer gas this has also led to an increased interest in nitrogen washout tests, despite the differences between these methods. The impact of...
متن کاملA Systematic Approach to Multiple Breath Nitrogen Washout Test Quality
BACKGROUND Accurate estimates of multiple breath washout (MBW) outcomes require correct operation of the device, appropriate distraction of the subject to ensure they breathe in a manner representative of their relaxed tidal breathing pattern, and appropriate interpretation of the acquired data. Based on available recommendations for an acceptable MBW test, we aimed to develop a protocol to sys...
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ژورنال
عنوان ژورنال: Journal of Applied Physiology
سال: 2020
ISSN: 8750-7587,1522-1601
DOI: 10.1152/japplphysiol.00841.2020